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![Image](http://www.npr.org/programs/atc/features/2005/may/wolf/wolf6kiss300.jpg)
A wolf's head is already larger than a human's head, so scaling it up would make it enormous.
![Image](http://www.npr.org/programs/atc/features/2005/may/wolf/wolf1camera300.jpg)
Wolves weigh half to a third as much as people because they have much narrower bodies and thinner, shorter legs. Much of a wolf's apparent volume is actually thick fur (up to 3 inches long). Still, like most quadrupedal animals, they're very strong for their size. It's a matter of leverage.
(I tend to give wolf form somewhat more human proportions, giving them heavier bodies and longer, thicker legs than a normal wolf, but that's a deliberate artistic decision. My werewolves aren't "really" wolves, but large, intelligent, wolflike creatures. Goldenwolf does something similar with her Kierrn.)